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0.2-10 L Benchtop Bioreactor System

One automated benchtop system that accommodates single-use bioreactors from 0.2-10 L in volume. 

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BIOREACTOR CONTROL SYSTEM

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  1. Heating Enclosure

  2. Perfusion Media Bag Hanger

  3. Rotating Bioreactor Stand

  4. Peristatic Pump (circulates media between perfusion media bag and bioreactor vessel)

  5. Enclosure Heater and Circulation Fan

  6. Touch Screen HMI

  7. Extendable Bag Hangers

  8. Peristatic Pumps

  9. Bioreactor Vessel Mounted on Rotating Stand (bioreactor is inverted to mix contents within vessel chamber)

  10. Refrigerated Compartment (contains stacked bag trays)

  11. Sliding Bag Hangers

  12. Compressed Gas Inlets (located on back of system)

  1. Heating Enclosure

  2. Perfusion Media Bag Hanger

  3. Rotating Bioreactor Stand

  4. Peristatic Pump (circulates media between perfusion media bag and bioreactor vessel)

  5. Enclosure Heater and Circulation Fan

  6. Touch Screen HMI

  7. Extendable Bag Hangers

  8. Peristatic Pumps

  9. Bioreactor Vessel Mounted on Rotating Stand (bioreactor is inverted to mix contents within vessel chamber)

  10. Refrigerated Compartment (contains stacked bag trays)

  11. Sliding Bag Hangers

  12. Compressed Gas Inlets (located on back of system)

SMALL FOOTPRINT, LARGE IMPACT

Ensuring Process Sterility 

The Membio bioreactor system comes with a fully-closed fluidics set that is

  • easy to install,

  • single use, and 

  • can be adapted to the needs of a wide range of processes.


Why is this important?
 

A fully-closed fluidics system de-risks manufacturing by reducing the risk of contamination.

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Fully Automated From Innoculation to Harvest

The Membio bioreactor control system can automatically inoculate, expand, sample, harvest, and transfer cells between vessels based on user-defined setpoints tied to in-process data.

This reduces human error and the risk of batch failure, while creating a unique and simple user experience

Harvest efficiencies of >97% are achievable through simple gravity-based draining.

DE-RISK MANUFACTURING

AN UNPRECEDENTED WAY TO GROW CELLS

SINGLE-USE BIOREACTOR VESSELS

  1. Gas Perfusion Inlet/Outlet

  2. Gas Perfusion Membranes

  3. Sensor Port (ex. O2, pH, temp)

  4. ​Vessel Chamber (where cells grow)

  5. Fluid Management Port

  6. Liquid Perfusion Membranes

  7. Liquid Perfusion Inlet/Outlet

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HIGH FLEXIBILITY, LOW RISK

Designed to Maximize Efficiency

MIMICKING THE PERFECT DESIGN

Capillaries distributed throughout the human body ensure that cells are never out of reach of the nutrients they need to grow, making it the most efficient nutrient delivery system.

 

Membio bioreactors recreate this system:

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Leveraging Nature's Design

Membio bioreactor vessels have gas and liquid perfusion systems that are precisely distributed throughout the vessel chamber so that, just like in the human body, cells are never out of reach of the critical gas and liquid nutrients they need to grow. 

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Effortless Scaling from 0.2-10 L

What does this mean?

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Directly transfer your process from one scale to another with minimal to no optimization

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The Membio bioreactor system focuses on maintaining the same microenvironment at every scale. This ensures consistent cell metabolism and growth across all sizes of Membio bioreactors.

SCALE UP, NOT OUT in 2 different ways:

DESIGNED TO SCALE UP, NOT OUT

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